|Type of Study
|Systematic review of (homogeneous) randomized
|Individual randomized controlled trials (with narrow
|Systematic review of (homogeneous) cohort studies
of "exposed" and "unexposed" subjects
|Individual cohort study / low-quality randomized
|Systematic review of (homogeneous) case-control studies
|Individual case-control studies
|Case series, low-quality cohort or case-control studies
|Expert opinions based on non-systematic reviews of
results or mechanistic studies
Critically-appraised individual articles and synopses include:
Two things to remember:
1. Studies in which randomization occurs represent a higher level of evidence than those in which subject selection is not random.
2. Controlled studies carry a higher level of evidence than those in which control groups are not used.
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