|• Be developed by a knowledgeable, multidisciplinary panel of experts and representatives from key affected groups
|• Consider important patient subgroups and patient values and preferences
|• Be based on an explicit and transparent process that minimizes distortions, biases, and conflicts of interest
|• Provide a clear explanation of the logical relationships between alternative care options and health outcomes
|• Provide ratings of the quality of evidence and the strength of recommendations
|• Be reconsidered and revised as appropriate when important new evidence warrants modifications of recommendations
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